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Browsing by Author "Ashraf, Ghulam Md"

Browsing by Author "Ashraf, Ghulam Md"

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  • Cholinesterase Inhibitors for Alzheimer's Disease 
    Kabir, Md Tanvir; Uddin, Md Sahab; Begum, Mst Marium; Thangapandiyan, Shanmugam; Rahman, Md Sohanur; Aleya, Lotfi; Mathew, Bijo; Ahmed, Muniruddin; Barreto, George E; Ashraf, Ghulam Md (Current Pharmaceutical Design, 2019)
    In the brain, acetylcholine (ACh) is regarded as one of the major neurotransmitters. During the advancement of Alzheimer's disease (AD) cholinergic deficits occur and this can lead to extensive cognitive dysfunction and ...
  • CNS Depressant Activities of Averrhoa carambola Leaves Extract in Thiopental-Sodium Model of Swiss Albino Mice 
    Akter, Aklima; Islam, Fahadul; Bepary, Sristy; . Al‑Amin, Md.; Begh, Md. Zamshed Alam; Islam, Md. Al Fahad Ul; Ashraf, Ghulam Md; Baeesa, Saleh Salem; Ullah, Mohammad Fahad (Daffodil International University, 2022-02-22)
    Psychological stress and anxiety have been linked to significant impairments of neurobiological functions. There is a wide range of conditions including neurological disorders such as Alzheimer’s disease and use of certain ...
  • Current Trends of Computational Tools in Geriatric Medicine and Frailty Management 
    Louka, Anna Maria; Tsagkaris, Christos; Christoforou, Panagiotis; Khan, Andleeb; Alexiou, Filia; Simou, Panagiota; Haranas, Loannis; Gkigkitzis, Loannis; Zouganelis, Georgios; Jha, Niraj Kumar; Uddin, Md Sahab; Shen, Bairong; Kamal, Mohammad A.; Ashraf, Ghulam Md; Alexiou, Athanasios (Daffodil International University, 2022-07-19)
    While frailty corresponds to a multisystem failure, geriatric assessment can recognize multiple pathophysiological lesions and age changes. Up to now, a few frailty indexes have been introduced, presenting definitions of ...
  • DeePred-BBB 
    Kumar, Rajnish; Sharma, Anju; Alexiou, Athanasios; Bilgrami, Anwar L.; Kamal, Mohammad Amjad; Ashraf, Ghulam Md (Daffodil International University, 2022-05-03)
    The blood-brain barrier (BBB) is a selective and semipermeable boundary that maintains homeostasis inside the central nervous system (CNS). The BBB permeability of compounds is an important consideration during CNS-acting ...
  • Dietary Alterations in Impaired Mitochondrial Dynamics Due to Neurodegeneration 
    Ashraf, Ghulam Md; Chatzichronis, Stylianos; Alexiou, Athanasios; Firdousi, Gazala; Kamal, Mohammad Amjad; Ganash, Magdah (Daffodil International University, 2022-07-11)
    Alzheimer’s disease is still an incurable disease with significant social and economic impact globally. Nevertheless, newly FDA-approved drugs and non-pharmacological techniques may offer efficient disease treatments. ...
  • Emerging Promise of Therapeutic Approaches Targeting Mitochondria in Neurodegenerative Disorders 
    Rahman, Md Mominur; Tumpa, Mst Afroza Alam; Rahaman, Md Saidur; Islam, Fahadul; Islam, Fahadul; Sutradhar, Popy Rani; Ahmed, Muniruddin; Alghamdi, Badrah S.; Hafeez, Abdul; Alexiou, Athanasios; Perveen, Asma; Ashraf, Ghulam Md (Emerald Publishing Limited, 2023-04-12)
    Mitochondria are critical for homeostasis and metabolism in all cellular eukaryotes. Brain mitochondria are the primary source of fuel that supports many brain functions, including intracellular energy supply, cellular ...
  • Estrogen Signaling in Alzheimer’s Disease 
    Uddin, Md. Sahab; Rahman, Md. Motiar; Jakaria, Md.; Rahman, Md. Sohanur; Hossain, Md. Sarwar; Islam, Ariful; Ahmed, Muniruddin; Mathew, Bijo; Omar, Ulfat Mohammed; Barreto, George E.; Ashraf, Ghulam Md (Molecular Neurobiology, Springer, 2020-04-15)
    Estrogens play a crucial physiological function in the brain; however, debates exist concerning the role of estrogens in Alzheimer’s disease (AD). Women during pre-, peri-, or menopause periods are more susceptible for ...
  • Exposure of Metal Toxicity in Alzheimer's Disease 
    Islam, Fahadul; Shohag, Sheikh; Akhter, Shomaya; Islam, Md. Rezaul; Sultana, Sharifa; Mitra, Saikat; Chandran, Deepak; Khandaker, Mayeen Uddin; Ashraf, Ghulam Md; Idris, Abubakr M.; Emran, Talha Bin; Cavalu, Simona (Daffodil International University, 2022-08-12)
    Metals serve important roles in the human body, including the maintenance of cell structure and the regulation of gene expression, the antioxidant response, and neurotransmission. High metal uptake in the nervous system ...
  • Free Radical Scavenging, Thrombolytic and Cytotoxic Effects of the Medicinal Herb, Crassocephalum Crepidioides 
    Kabir, Md. Tanvir; Samiha, Mayesha; Yasmin, Hasina; Rahman, Mohammed S.; Rahman, Md. Sohanur; Ashraf, Ghulam Md; Akter, Raushanara (Research Journal of Pharmacy and Technology, 2021)
    Crassocephalum crepidioides belongs to the Asteraceae family and the leaves of the plant were used in the phytochemical screening. The objective of this study was phytochemical analysis of C. crepidioides in order to ...
  • Hutchinson-Gilford Progeria Syndrome 
    Rahman, Md Mominur; Ferdous, Kazi Sayma; Ahmed, Muniruddin; Islam, Mohammad Touhidul; Khan, Md Robin; Perveen, Asma; Ashraf, Ghulam Md; Uddin, Md Sahab (Scopus, 2021)
    Lamin A/C encoded by the LMNA gene is an essential component for maintaining the nuclear structure. Mutation in the lamin A/C leads to a group of inherited disorders is known as laminopathies. In the human body, there are ...
  • Investigation and Drug Design for Novel Molecules From Natural Products As Inhibitors for Controlling Multiple Myeloma Disease Using In-Silico Tools 
    Zari, Ali; Kurdi, Lina A. F.; Jaber, Fatima A; Alghamdi, Khalid M S; Zari, Talal A; Bahieldin, Ahmed; Hakeem, Khalid Rehman; Alnahdi, Hanan S.; Edris, Sherif; Ashraf, Ghulam Md (Taylor & Francis Group, 2024-01-03)
    The demand for energy across the world is constantly rising. Therefore remarkable endeavors have been dedicated to the development of high-performance energy storage devices with nanoscale design and hybrid approaches. ...
  • Repurposing Food Molecules as a Potential BACE1 Inhibitor for Alzheimer's Disease 
    Mukerjee, Nobendu; Das, Anubhab; Jawarkar, Rahul D.; Maitra, Swastika; Das, Padmashree; Castrosanto, Melvin A.; Paul, Soumyadip; Samad, Abdul; Zaki, Magdi E. A.; Al-Hussain, Sami A.; Masand, Vijay H.; Hasan, Mohammad Mehedi; Bukhari, Syed Nasir Abbas; Perveen, Asma; Alghamdi, Badrah S.; Alexiou, Athanasios; Kamal, Mohammad Amjad; Dey, Abhijit; Malik, Sumira; Bakal, Ravindra L.; Abuzenadah, Adel Mohammad; Ghosh, Arabinda; Ashraf, Ghulam Md (Daffodil International University, 2022-08-22)
    Alzheimer’s disease (AD) is a severe neurodegenerative disorder of the brain that manifests as dementia, disorientation, difficulty in speech, and progressive cognitive and behavioral impairment. The emerging therapeutic ...

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