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Browsing by Author "Gupta, Jeetendra Kumar"

Browsing by Author "Gupta, Jeetendra Kumar"

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  • Alkaloid-based modulators of the PI3K/Akt/mTOR pathway for cancer therapy: Understandings from pharmacological point of view 
    Mokhfi, Fatima Zohra; Amin, Md Al; Zehravi, Mehrukh; Sweilam, Sherouk Hussein; Arjun, Uppuluri Varuna Naga Venkata; Gupta, Jeetendra Kumar; Vallamkonda, Bhaskar; Balakrishnan, Anitha; Challa, Manjula; Singh, Jyoti; Prasad, P. Dharani; Ali, Syed Salman; Ahmad, Irfan; Doukani, Koula; Emran, Talha Bin (Scopus, 2024)
    This review aims to summarize the role of alkaloids as potential modulators of the PI3K/Akt/mTOR (PAMT) pathway in cancer therapy. The PAMT pathway plays a critical role in cell growth, survival, and metabolism, and its ...
  • Alkaloid-based Modulators of the PI3K/AKT/MTOR Pathway for Cancer Therapy: Understandings from Pharmacological Point of View 
    Mokhfi, Fatima Zohra; Amin, Md Al; Zehravi, Mehrukh; Sweilam, Sherouk Hussein; Arjun, Uppuluri Varuna Naga Venkata; Gupta, Jeetendra Kumar; Vallamkonda, Bhaskar; Balakrishnan, Anitha; Challa, Manjula; Singh, Jyoti; Prasad, Dharani; Ali, Syed Salman; Ahmad, Irfan; Doukani, Koula; Emran, Talha Bin (Elsevier, 2024-10-01)
    This review aims to summarize the role of alkaloids as potential modulators of the PI3K/Akt/mTOR (PAMT) pathway in cancer therapy. The PAMT pathway plays a critical role in cell growth, survival, and metabolism, and its ...
  • Bioactive Molecules From Terrestrial and Seafood Resources in Hypertension Treatment 
    Islam, Md. Rezaul; Dhar, Puja Sutro; Akash, Shopnil; Syed, Sabeena Hussain; Gupta, Jeetendra Kumar; Gandla, Kumaraswamy; Akter, Muniya; Rauf, Abdur; Hemeg, Hassan A.; Anwar, Yasir; Aljohny, Bassam Oudh; Wilairatana, Polrat (Springer Nature Limited, 2023-10-30)
    Hypertension (HTN), a complex cardiovascular disease (CVD), significantly impacts global health, prompting a growing interest in complementary and alternative therapeutic approaches. This review article seeks to provide ...
  • Identifying Potent Breast Cancer Inhibitors Against ERα Target Using Pharmacophore Model, 3D-QSAR and MD Studies 
    Rajagopal, Kalirajan; Arumugasamy, Pandiselvi; Raman, Kannan; Jupudi, Srikanth; Byran, Gowramma; Gupta, Jeetendra Kumar; Prema, S.; Kankate, Rani S.; Elansari, Lamyae; Hossain, Nazmul (Scopus, 2024)
    the current investigation, 109 known ERα inhibitors have been developed in the current research; pharmacophore modeling, Molecular docking, MM-GBSA, and MD study have been performed to investigate the binding affinity of ...
  • Identifying Potent Breast Cancer Inhibitors Against ERα Target Using Pharmacophore Model, 3D-QSAR and MD Studies 
    Rajagopal, Kalirajan; Arumugasamy, Pandiselvi; Raman, Kannan; Jupudi, Srikanth; Byran, Gowramma; Gupta, Jeetendra Kumar; Kankate, Prema, Rani S.; Elansari, Lamyae; Hossain, Nazmul (John Wiley & Sons, 2024-08-24)
    The current investigation, 109 known ERα inhibitors have been developed in the current research; pharmacophore modeling, Molecular docking, MM-GBSA, and MD study have been performed to investigate the binding affinity of ...
  • Recent Perspective on the Potential Role of Phytocompounds in the Prevention of Gastric Cancer 
    Islam, Md. Rezaul; Rauf, Abdur; Akash, Shopnil; Kumer, Ajoy; Hussain, Md Sadique; Akter, Smrity; Gupta, Jeetendra Kumar; Ansari, L.H. Thameemul; Raj, Mir Md. Mahfoj Islam; Emran, Talha Bin; Aljohani, Abdullah S.M.; Abdulmonem, Waleed Al; Thiruvengadam, Rekha; Thiruvengadam, Muthu (Elsevier, 2023-12-15)
    Gastric cancer (GC) is a serious global health concern. GC is a form of cancer that advances through the stomach lining. Therefore, there is a requirement to explore novel preventive strategies for GC. A novel study indicated ...
  • Research Progress of Indole Alkaloids: Targeting MAP Kinase Signaling Pathways in Cancer Treatment 
    Al Amin, Md.; Emran, Talha Bin; Khan, Jishan; Zehravi, Mehrukh; Sharma, Indu; Patil, Anasuya; Gupta, Jeetendra Kumar; Jeslin, D.; Krishnan, Karthickeyan; Das, Rajib; Nainu, Firzan; Ahmad, Irfan; Wilairatana, Polrat (MDPI Publications, 2023-11-07)
    Cancer is the leading cause of morbidity and mortality in people throughout the world. There are many signaling pathways associated with cancerous diseases, from which the Mitogen-activated protein kinase (MAPK) pathway ...
  • Resveratrol: A Natural Compound Targeting the PI3K/Akt/mTOR Pathway in Neurological Diseases 
    Biswajit Kumar Utpal, Biswajit Kumar; Mokhfi, Fatima Zohra; Zehravi, Mehrukh; Sweilam, Sherouk Hussein; Gupta, Jeetendra Kumar; Kareemulla, Shaik; Darwin, Ronald; Rao, A. Anka; Kumar, Voleti Vijaya; Pavankumar Krosuri, Pavankumar; Prasad, Dharani; Khan, Sharukh L.; Roy, Sajib Chandra; Rab, Safia Obaidur; Alshehri, Mohammed Ali; Emran, Talha Bin (Springer Nature, 2024-11-23)
    Neurological diseases (NDs), including neurodegenerative disorders and acute injuries, are a significant global health concern. The PI3K/Akt/mTOR pathway, a crucial signaling cascade, is responsible for the survival of ...

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