Browsing by Author "Ibrahim, Ibrahim Abdel Aziz"

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Coumarin-Based Sulfonamide Derivatives As Potential DPP-IV Inhibitors

Vawhal, Pallavi Kishor; Jadhav, Shailaja B.; Kaushik, Sumit; Panigrahi, Kahnu Charan; Nayak, Chandan; Urmee, Humaira; Khan, Sharuk L.; Siddiqui, Falak A.; Islam, Fahadul; Eftekhari, Aziz; Alzahrani, Abdullah R.; Azlina, Mohd Fahami Nur; Sarker, Md. Moklesur Rahman; Ibrahim, Ibrahim Abdel Aziz (MDPI Publications, 2023-01-19)

Recent research on dipeptidyl peptidase-IV (DPP-IV) inhibitors has made it feasible to treat type 2 diabetes mellitus (T2DM) with minimal side effects. Therefore, in the present investigation, we aimed to discover and ...
The Design, Synthesis, and Evaluation of Diaminopimelic Acid Derivatives as Potential dapF Inhibitors Preventing Lysine Biosynthesis for Antibacterial Activity

Shaikh, Mohd Sayeed; Kale, Mayura A.; Muralidharan, V.; Venkatachalam, T.; Ali, Syed Sarfaraz; Islam, Fahadul; Khan, Sharuk L.; Siddiqui, Falak A.; Urmee, Humaira; Tapadiya, Ganesh G.; Dhawale, Sachin A.; Ming, Long Chiau; Ibrahim, Ibrahim Abdel Aziz; Alzahrani, Abdullah R.; Sarker, Md. Moklesur Rahman; Azlina, Mohd Fahami Nur (MDPI Publications, 2022-12-28)

We created thiazole and oxazole analogues of diaminopimelic acid (DAP) by replacing its carboxyl groups and substituting sulphur for the central carbon atom. Toxicity, ADME, molecular docking, and in vitro antimicrobial ...

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