Scientific Investigation of the Anti-Stress Potential of Selected Herbal Plants in Heat-Induced Stressed Rats

Abstract

Stress is a state of mental strain for a specific person experiencing issues with their social and environmental well-being, which may result in a variety of illnesses. Stress is a factor in sickness and disease in 90% of cases. Body's natural functions and physical performance might be affected by stress. The study is designed to investigate the effects of herbs like rosemary, cinnamon and aloe vera in reducing stress level by determining the blood glucose level and serum cortisol level. And to find out the effects of anti-depressant and anxiolytic drugs on blood glucose and serum cortisol level. Cardiac puncture method was used for blood collection and spectrophotometric method was used to detect the blood glucose and cortisol level. The blood glucose level for herbal sample and standard groups were 6.1± 1.18 & 5.07± 0.208 mmol/L respectively where control group was 4.3 ± 0.321 mmol/L. Serum cortisol level 1.06± 0.23&0.92± 0.02 ug/dl for herbal and standard group drugs where 1.67± 0.499 ug/dl for control group. Morphological study of spleen was done to evaluate and compare the effectiveness of herbal and standard drugs against and the spleen mass of rats in the control group was 0.25 0.011 gm, while those in the standard group were 0.30 0.009 gm and those in the herbal combination group were 0.32 0.015 gm. The control group had a decrease in spleen size as a result of stress induction, whereas the other two groups saw substantial growth. Presents study indicates that herbal plants have the ability to reduce stress in normal range but further study is necessary to support theses statement.