Abstract:
Subfertility or infertility is a significant societal and psychological burden on couples,
particularly on African women. According to estimates, female factors and unexplained
infertility typically account for 50–80% of cases of infertility in Nigeria, necessitating a
review of the different research studies. The various causative variables that contribute to
female infertility were examined in this assessment, and an effort was made to update the
knowledge already on hand regarding its treatment. The primary goal of this review is to
produce data that could be used as guidelines in assessing female infertility. According to
the literature reviewed on female infertility, some of the suggested good preventive
measures to deal with infertility between many infertile women include a loss of 5–10% of
body weight in obese an ovulatory infertile woman, keeping up an active lifestyle,
preventative measures and prompt treatment of sexually transmitted diseases, and not
delaying parenthood. Letrozole and anastrozole are examples of aromatase inhibitors that
block estradiol biosynthesis, lessen estradiol impact on the hypothalamus-pituitary, and
raise the production of FSH in PCOS-afflicted women. Clomiphene intolerant women with
PCOS are those who have tried normal clomiphene doses but still have not been able to
ovulate. To lowering insulin levels is a treatment objective for PCOS-affected women. An
oral biguanide antihyperglycemic medication called metformin has been authorized for the
management of type 2 diabetes mellitus.
