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Marine Macrolides To Tackle Antimicrobial Resistance of Mycobacterium tuberculosis

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dc.contributor.author S., Sukamto
dc.contributor.author Mamada, Sukamto S.
dc.contributor.author Nainu, Firzan
dc.contributor.author Masyita, Ayu
dc.contributor.author Frediansyah, Andri
dc.contributor.author Utami, Rifka Nurul
dc.contributor.author Salampe, Mirnawati
dc.contributor.author Emran, Talha Bin
dc.contributor.author Lima, Clara Mariana Gonçalves
dc.contributor.author Chopra, Hitesh
dc.contributor.author Gandara, Jesus Simal
dc.date.accessioned 2023-06-26T06:01:45Z
dc.date.available 2023-06-26T06:01:45Z
dc.date.issued 22-11-01
dc.identifier.uri http://dspace.daffodilvarsity.edu.bd:8080/handle/123456789/10808
dc.description.abstract Tuberculosis has become a major health problem globally. This is worsened by the emergence of resistant strains of Mycobacterium tuberculosis showing ability to evade the effectiveness of the current ant mycobacterial therapies. Therefore, the efforts carried out to explore new entities from many sources, including marine, are critical. This review summarizes several marine-derived macrolides that show promising activity against M. tuberculosis. We also provide information regarding the biosynthetic processes of marine macrolides, including the challenges that are usually experienced in this process. As most of the studies reporting the ant mycobacterial activities of the listed marine macrolides are based on in vitro studies, the future direction should consider expanding the trials to in vivo and clinical trials. In addition, in silico studies should also be explored for a quick screening on marine macrolides with potent activities against mycobacterial infection. To sum up, macrolides derived from marine organisms might become therapeutical options for tackling ant mycobacterial resistance of M. tuberculosis. en_US
dc.language.iso en_US en_US
dc.publisher Scopus en_US
dc.subject Therapeutic en_US
dc.subject Health care en_US
dc.title Marine Macrolides To Tackle Antimicrobial Resistance of Mycobacterium tuberculosis en_US
dc.type Article en_US


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