Free Radical Scavenging Activities of Some Indigenous Plants of Bangladesh

Abstract

Four indigenous plant, Bryophyllum daigremontianum (Raym.), Coccinea cordifolia (Linn.), Litsea glutinosa (Lour.) and Micromelum minutum (G. Forst.) have been investigated for their antioxidant activity. The extractives were subjected to assay by using 1,1-diphenyl-2-picrylhydrazyl (DPPH) for evaluation of free radical scavenging property. The IC50 value of the organic extracts ranged from 336.45 to 23.85 μg/ml. The aqueous soluble fraction of L. glutinosa demonstrated potent free radical scavenging activity (IC50-23.85μg/ml) as compared to tert-butyl- 1-hydroxytoluene (standard) that showed an ICso value of 34.89 μg/ml. The results primarily suggest the presence of potent oxidation inhibitory principles in the leaves of L. glutinosa.