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Evaluation of Wound Healing Activity (Excision Wound Model) of Ointment Prepared from Infusion Extract of Polyherbal Tea Bag Formulation in Diabetes-Induced Rats

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dc.contributor.author Quazi, Aamir
dc.contributor.author Patwekar, Mohsina
dc.contributor.author Patwekar, Faheem
dc.contributor.author Mezni, Amine
dc.contributor.author Mezni, Amine
dc.contributor.author Ahmad, Irfan
dc.contributor.author Islam, Fahadul
dc.date.accessioned 2024-03-25T05:41:22Z
dc.date.available 2024-03-25T05:41:22Z
dc.date.issued 2022-06-06
dc.identifier.uri http://dspace.daffodilvarsity.edu.bd:8080/handle/123456789/11819
dc.description.abstract In the present investigation, Ichnocarpus frutescens, Ficus dalhousiae, Crateva magna, Alpinia galanga, and Swertia chirata plants were selected to formulate polyherbal tea bag. The infusion obtained from these polyherbal tea bags was used to formulate 5% and 10% ointment formulation to perform its wound healing activity. The excision wound model was used to assess the wound healing activity in diabetic as well nondiabetic rats. The mean percentage closure of wound area was calculated on the 3rd, 6th, 9th, 12th, 15th, 18th, and finally 21st day. The wound healing activity of formulation was found to be significantly compared with that of the reference standard and untreated groups. The percentages of closure of excision wound area on the 21st day in diabetic animals treated with ointment formulations (F1 and F2) were found to be 93.91 ± 1.65% and 99.12 ± 5.21% respectively, whereas the chloramphenicol sodium drug solution was found to be 99.81 ± 3.16%. The percentages of closure of excision wound area in nondiabetic animals treated with ointment formulations (F1 and F2) were found to be 96.81 ± 2.04% and 98.13 ± 1.14%, respectively, whereas the chloramphenicol sodium drug solution was found to be 99.15 ± 1.41% at 21st day. Therefore, from the above results, we have concluded that this polyherbal ointment can be used clinically for the treatment of diabetic and nondiabetic wounds. en_US
dc.language.iso en_US en_US
dc.publisher Daffodil International University en_US
dc.subject Diabetes en_US
dc.subject Diseases en_US
dc.subject Treatment en_US
dc.title Evaluation of Wound Healing Activity (Excision Wound Model) of Ointment Prepared from Infusion Extract of Polyherbal Tea Bag Formulation in Diabetes-Induced Rats en_US
dc.type Article en_US


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