Abstract:
Proton pump inhibitors (PPIs) are widely prescribed medications for the management of
various gastrointestinal disorders. This survey aims to investigate the knowledge and
perceptions of patients with gastrointestinal disorders regarding the extended use of PPIs.
The study employs a cross-sectional design, utilizing a structured questionnaire
administered to a diverse sample of patients diagnosed with gastrointestinal disorders who
are currently undergoing long-term PPI therapy. The survey assesses participants'
awareness of the indications for PPI use, understanding of potential side effects and risks
associated with prolonged usage, and their perceptions of the necessity for continued
medication. In this investigation most of the responders (77%) have been affected
gastrointestinal disease. Majority of the responders 44% replied they have been diagnosed
gastrointestinal disease from less than one year, 31% responders replied they have been
diagnosed gastrointestinal disease from 1-5 years. Among them majority participants 30%
responded that they have been suffered Gastroesophageal reflux disease (GERD). Also
20% participant’s responded that they have been suffered change in normal bowel habits.
According to the survey, most of the responders (78%) have been said they haven’t aware
about complication of long term use of Proton Pump Inhibitor (PPI). 32% participants
replied that they have been suffered Bone fractures, 25% responded suffered Clostridium
difficile-associated diarrhea, and 18% replied they suffered chronic kidney disease due to
long term use of Proton Pump Inhibitor (PPI). In this investigation, maximum participants
55% replied that they have been taken PPI daily, 22% replied 2-3 times a week and 18%
replied 4-5 times a week taken Proton Pump Inhibitor. Majority of the participants 92%
replied that they have been taken regularly PPI without doctor prescribing. Here
demonstrate that 40% responders replied they have been PPI in morning empty stomach,
25% replied they have been taken PPI at night 30 min before and 30% responders taken
after meal. Ultimately, this survey serves as a valuable foundation for future research and
interventions aimed at enhancing patient education and understanding regarding the long-
term use of proton pump inhibitors.
