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Cytokines and Their Role as Immunotherapeutics and Vaccine Adjuvants: The Emerging Concepts

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dc.contributor.author Rahman, Tanjilur
dc.contributor.author Das, Ayan
dc.contributor.author Abir, Mehedy Hasan
dc.contributor.author Nafiz, Iqbal Hossain
dc.contributor.author Mahmud, Aar Rafi
dc.contributor.author Sarker, Md. Rifat
dc.contributor.author Emran, Talha Bin
dc.contributor.author Hassan, Mohammad Mahmudul
dc.date.accessioned 2024-05-11T10:09:01Z
dc.date.available 2024-05-11T10:09:01Z
dc.date.issued 2023-09-15
dc.identifier.uri http://dspace.daffodilvarsity.edu.bd:8080/handle/123456789/12312
dc.description.abstract Cytokines are a protein family comprising interleukins, lymphokines, chemokines, monokines and interferons. They are significant constituents of the immune system, and they act in accordance with specific cytokine inhibiting compounds and receptors for the regulation of immune responses. Cytokine studies have resulted in the establishment of newer therapies which are being utilized for the treatment of several malignant diseases. The advancement of these therapies has occurred from two distinct strategies. The first strategy involves administrating the recombinant and purified cytokines, and the second strategy involves administrating the therapeutics which inhibits harmful effects of endogenous and overexpressed cytokines. Colony stimulating factors and interferons are two exemplary therapeutics of cytokines. An important effect of cytokine receptor antagonist is that they can serve as anti-inflammatory agents by altering the treatments of inflammation disorder, therefore inhibiting the effects of tumour necrosis factor. In this article, we have highlighted the research behind the establishment of cytokines as therapeutics and vaccine adjuvants, their role of immunotolerance, and their limitations. en_US
dc.language.iso en_US en_US
dc.publisher IEEE en_US
dc.subject Cytokines en_US
dc.subject Immune responses en_US
dc.title Cytokines and Their Role as Immunotherapeutics and Vaccine Adjuvants: The Emerging Concepts en_US
dc.type Article en_US


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