Phytochemical Screening, Assessment of Thrombolytic and Antistress Activity of Methanol Extract of Terminalia Arjuna and Oxalis Corniculata

Abstract

The present study provides a comprehensive overview of the investigation into the potential pharmacological properties of Terminalia Arjuna Bark and Oxalis Corniculata and their combine extract. this research investigates the traditional applications and phytochemical constituents of the substance, with an emphasis on its potential for the treatment of stress-related disorders and thrombus disintegration. Through experimental methodologies including plant collection, extraction, and biochemical analysis, the study evaluates the thrombolytic activity and effects on cortisol levels, blood glucose, and C-reactive protein (CRP) levels in animal models. Results indicate that Arjun tree bark extract and combine extract both exhibits reducing serum cortisol, blood glucose and CRP levels, thereby indicating anti-stress properties and have mild thrombolytic activity, Amrul extract shows mild thrombolytic activity and have little bit effects on changing cortisol and CRP levels. The lysis results for the control and standard were 7.2% and 76%, respectively, as the investigation revealed. The three samples contained 29.1%, 27.5%, and 33.5%. Furthermore, the serum cortisol levels of the standard and herbal groups were 2.94 ± 0.4, 3.01 ± 0.25, 3.36 ± 0.68, and 2.14 ± 0.22 ug/dl, respectively, while the control group's level was 3.79 ± 0.56 ug/dl. The investigation demonstrated that the following values were obtained for the control and standard: glucose and CRP, respectively: 4.17 ± 0.71 and 6.39 ± 0.59, and 3.54 ± 0.31 and 3.85 ± 0.95. CRP 1.91 ± 0.59, 3.32 ± 0.36, 2.73 ± 0.95, and glucose 4.55 ± 0.88, 5.76 ± 1.69, and 2.11 ± 0.42 were detected in the sample. The results suggest that the combine sample have antistress properties, as they reduce serum cortisol and CRP levels. Furthermore, the arjun bark and amrul extract exhibits the potential to regulate Serum cortisol and CRP levels, which serves to emphasize its therapeutic advantages. The effects of anti-stress and its related activities were investigated through the examination of serum cortisol levels, cortisol-induced C-reactive protein (CRP), and random blood sugar (RBS) levels in a design analysis that was divided into a single section.