Antihyperlipidemic, Antihyperglycemic and Hepatoprotective Activities of Cabbage, Ispaghula & Yogurt: An Experimental Analysis

Abstract

This study investigates the potential therapeutic effects of cabbage (Brassica oleracea) and ispaghula (Plantago ovata) through experimental analysis of their antihyperlipidemic, antihyperglycemic, and antihepatotoxic properties. The research aimed to explore the traditional medicinal applications of these plants and evaluate their scientific basis. In the experimental analysis, both aqueous extracts of cabbage and ispaghula were prepared and administered to laboratory animals subjected to induced hyperlipidemia, hyperglycemia, and hepatotoxicity. Parameters including serum lipid profiles, blood glucose levels, and liver function tests were assessed to determine the efficacy of the extracts. The Sample group's weight raised by 0.46 grams, compared to a 0.38 gm weight change in the Standard group. The SGPT (ALT) levels observed in the control and sample groups, with values of 39.77 ± 1.54 (UI/L) and 37.55 ± 3.96 (UL/L), correspondingly, are normal. Lowering SGPT levels proved successful for the sample (fiber) group. The control and sample group values are 7.65 mmol/L and 6.1 mmol/L, respectively, versus the standard value after two hours, using glucose as the tolerance level. The sample (fiber) group was able to reduce the levels of OGTT. The total cholesterol level in the fiber combination group was 41.45 ± 2.57 mg/dl, whereas it was 67.56 ± 2.22 mg/dl in the control group. Triglyceride levels in the sample were 107.78 ± 3.24 mg/dl, while the control had a drop of 15.25 mg/dl to 123.03 ± 2.97 mg/dl. After a month of therapy, conclusive results demonstrated no negative effects of nominal fats on the experimental rats.