Haque, M. Akiful; Marathakam, Akash; Rana, Ritesh; Almehmadi, Samar J.; Tambe, Vishal B.; Charde, Manoj S.; Islam, Fahadul; Siddiqui, Falak A.; Culletta, Giulia; Almerico, Anna Maria; Tutone, Marco; Khan, Sharuk L.
(MDPI Publications, 2023-01-04)
The present work describes the design and development of seventeen pyrimidine-clubbed benzimidazole derivatives as potential dihydrofolate reductase (DHFR) inhibitors. These compounds were filtered by using ADMET, drug-likeness ...