Browsing Articles by Subject "Drug design"

Now showing items 1-5 of 5

Computational Modeling and Analysis of Gene Regulatory Interaction Network for Metabolic Disorder: a Bioinformatics Approach

Ahmed, Md. Liton; Islam, Md. Rakibul; Paul, Bikash Kumar; Ahmed, Kawsar; Bhuyian, Touhid (Biointerface Research in Applied Chemistry, 2020-04-22)

In this study, we generate a PPI network and co-regulatory networks to understand the mechanisms of metabolic disorder more clearly. This study also analyzes the relevance of genes that are responsible for Cardiovascular ...
Computer-Aided Drug Design-Based System Pharmacology Applications for the Treatment of Diabetes Mellitus

Bibi, Shabana; Hasan, Mohammad Mehedi; Hossain, Md. Shahadat; Khan, Muhammad Saad; Yousafi, Qudsia; Islam, Fahadul; Chopra, Hitesh; Kamal, Mohammad Amjad (Elsevier, 2023-06-15)

Diabetes mellitus is a very complicated and long-term disease. Diabetic patients are always at risk of creating more complicated diseases in a very short time, as the damage of body organs is very fast if the situation ...
A Drug Design Strategy Based on Molecular Docking and Molecular Dynamics Simulations Applied to Development of Inhibitor Against Triple-Negative Breast Cancer by Scutellarein Derivatives

Akash, Shopnil; Aovi, Farjana Islam; Azad, Md. A. K.; Kumer, Ajoy; Chakma, Unesco; Islam, Md. Rezaul; Mukerjee, Nobendu; Rahman, Md. Mominur; Bayıl, Imren; Rashid, Summya; Sharma, Rohit (PLOS, 2023-10-12)

Triple-negative breast cancer (TNBC), accounting for 10–15% of all breast malignancies, is more prevalent in women under 40, particularly in those of African descent or carrying the BRCA1 mutation. TNBC is characterized ...
Investigation of Protein-Protein Interactions and Hotspot Region on the NSP7-NSP8 Binding Site in NSP12 of SARS-CoV-2

Neto, José Xavier Lima; Bezerra, Katyanna Sales; Barbosa, Emmanuel Duarte; Araujo, Roniel Lima; Galvão, Douglas Soares; Lyra, Marcelo Leite; Oliveira, Jonas Ivan Nobre; Akash, Shopnil; Jardan, Yousef A Bin; Nafidi, Hiba-Allah; Bourhia, Mohammed; Fulco, Umberto Laino (PubMed Central Press, 2024-01-18)

Background: The RNA-dependent RNA polymerase (RdRp) complex, essential in viral transcription and replication, is a key target for antiviral therapeutics. The core unit of RdRp comprises the nonstructural protein NSP12, ...
Ligand-Based Drug Design of Pinocembrin Derivatives Against Monkey-Pox Disease

Akash, Shopnil; Bibi, Shabana; Yousafi, Qudsia; Ihsan, Awais; Mustafa, Riaz; Farooq, Umar; Kabra, Atul; Alanazi, Mohammad M.; Alanazi, Ashwag S.; Kamaly, Omkulthom Al (Elsevier, 2023-09-06)

Severe pathogen infections, such as Monkeypox disease caused by the Monkeypox virus, easily spread in different animals and then into humans. There is an urge for novel therapeutic options, such as medicine/vaccine development ...

Browsing Articles by Subject "Drug design"

Browsing Articles by Subject "Drug design"

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