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Synthesis, Characterization and Biological Activity of Mixed hydroxyl

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dc.contributor.author Bamigboye, Mercy O.
dc.contributor.author Ejidike, Ikechukwu P.
dc.contributor.author Obaleye, Joshua A.
dc.contributor.author Lawal, Misitura
dc.date.accessioned 2021-04-08T10:12:07Z
dc.date.available 2021-04-08T10:12:07Z
dc.date.issued 2021-01-18
dc.identifier.issn 1818-5878
dc.identifier.issn 2408-8498
dc.identifier.uri http://dspace.daffodilvarsity.edu.bd:8080/handle/123456789/5558
dc.description.abstract A series of new mixed anthranilic acid – ethambutol complexes [Co(ETB)(Ant)Cl2] (1), [Cd(ETB)(Ant)Cl2] (2), and [Cu(ETB)(Ant)Cl2] (3) where ETB= Ethambutol and Ant= Anthranilic acid, were synthesized by refluxing method and characterized using spectroscopic techniques such as infrared and ultraviolet/visible, elemental analysis, conductivity measurement and magnetic susceptibility. The ligands act as bidentate type coordinating to the central metal ion through the oxygen of the hydroxyl group and nitrogen of the amine group. Octahedral, square planar and tetrahedral geometry has been assigned to the Co(II), Cd(II) and Cu(II) complexes respectively. Towards the in vitro biological potentials, the ligands and the metal complexes were screened for antibacterial, antioxidant and antitubercular activities. The complexes were found to have an increased activity compared to their free parent ligands. This research work concluded that the mixed metal complexes of anthranilic acid – ethambutol showed promising activity against the selected organisms and as such exhibit candidates for the treatment of ailments. en_US
dc.language.iso en_US en_US
dc.publisher Daffodil International University en_US
dc.subject Metal Complexes en_US
dc.subject Antitubercular en_US
dc.title Synthesis, Characterization and Biological Activity of Mixed hydroxyl en_US
dc.title.alternative Amine Group Metal Drug Complexes en_US
dc.type Article en_US

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