Abstract:
Anthelmictic activity of crude gynura procumbens leaves extract was evaluated using adult
earthwarms. Gynura procumbens (Lour.) Merr. (Family Asteraceae) is a medicinal plants often found in
tropical Asian countries such as China, Thailand, Indonesia, Malaysia, Vietnam. Traditionally, it is widely
used in a wide variety of countries to treat a wide variety of health disorders such as kidney discomfort,
rheumatism, diabetes mellitus, constipation and hypertension. On the basis of traditional uses of G.
procumbens plant’s leaves , it seems to possess high therapeutic effect for treatment of various
diseases making it a target for pharmacological studies aiming to validate and provide scientific
evidence for the traditional claims of its efficacy. For anthelmintic activity standard albandazole
preparation 15mg/ml showed paralysis time 11.8 and death time 20.6. The extract of G. Procumbens
25mg/ml (paralysis time 36.4 and death time 52.4), 50mg/ml(paralysis time 22 and death time 41) and
100mg/ml (paralysis time 16 and death time 26). The results of present study specify that the ethanolic
extract significantly indicate paralysis and also caused death of worms in dose dependent manner.