In Vitro Anthelmintic Activity Ethanolic Leaves Extract of Gynura Procumbens, a Prospective Medicinal Plant

Abstract

Anthelmictic activity of crude gynura procumbens leaves extract was evaluated using adult earthwarms. Gynura procumbens (Lour.) Merr. (Family Asteraceae) is a medicinal plants often found in tropical Asian countries such as China, Thailand, Indonesia, Malaysia, Vietnam. Traditionally, it is widely used in a wide variety of countries to treat a wide variety of health disorders such as kidney discomfort, rheumatism, diabetes mellitus, constipation and hypertension. On the basis of traditional uses of G. procumbens plant’s leaves , it seems to possess high therapeutic effect for treatment of various diseases making it a target for pharmacological studies aiming to validate and provide scientific evidence for the traditional claims of its efficacy. For anthelmintic activity standard albandazole preparation 15mg/ml showed paralysis time 11.8 and death time 20.6. The extract of G. Procumbens 25mg/ml (paralysis time 36.4 and death time 52.4), 50mg/ml(paralysis time 22 and death time 41) and 100mg/ml (paralysis time 16 and death time 26). The results of present study specify that the ethanolic extract significantly indicate paralysis and also caused death of worms in dose dependent manner.