A Review on Indigenous Plants and Their Phytochemicals Used for the Prevention and Treatment of Alzheimer's Disease (AD)

Abstract

As a devastating neurological ailment, Alzheimer's disease (AD) requires significant research on appropriate treatment alternatives. The effects of plant extracts on the reduction of AD symptoms have been thoroughly investigated. An important measure of naturally occurring substances and plant extracts with the ability to inhibit the enzyme AChE have been found as a result of the fact that naturally-occurring molecules from plants are thought to be a potential source of novel inhibitors, which, in accordance with the cholinergic hypothesis raises the brain's acetylcholine levels, which enhances cholinergic function. functions in Alzheimer's patients and reduces the symptoms of this neurological condition. Presented here highlights of around 35 studies in all, representing the most significant report papers between 2006 and 2022. plant-derived substances, plant extracts, and essential oils were discovered to cause AChE inhibition in the first semester. These impacts are brought on by plant extracts from a few different species, including Ginkgo Biloba, Corydalis (Papaveraceae), Stephania venosa (Menispermaceae), Catharanthus roseus (Apocynaceae), Ervatamia hainanensis (Apocynaceae) stems, Curcuma longa, Bacopa monnieri etc. There are many bioactive plants in our country which can cure Alzheimer’s disease by proper using this plant compound. So we should do more research on these bioactive plants.