A Review on Parkinson’s Disease

Abstract

The neurodegenerative condition Parkinson's disease (PD) is rather prevalent. It is progressive and neurodegenerative, with symptoms including impaired balance, walking, and falls even at the time of diagnosis. Variables such as age, family history, pesticide exposure, and environmental factors are linked to the development of idiopathic Parkinson's Disease, which is caused by the pathophysiological loss or degeneration of dopaminergic neurons in the substantia nigra of the midbrain. Improvements in the knowledge of the disease's pathophysiology have been made in recent years. In addition to the more well-known motor problems, it has been more clear that the condition may also be linked to major non-motor abnormalities. There is mounting circumstantial evidence that certain existing therapies for PD may have a neuroprotective impact, although this has yet to be definitively shown. Even though PD has no known cure, it may be managed in a number of ways if caught early. Additional therapeutic options become available as the illness advances; nevertheless, late-stage motor problems and non-motor symptoms remain very tough to manage, and future discoveries in PD are anticipated to center on the notion of disease-modifying medications that provide neuroprotection.