Isolation and Characterization of Antibacterial Metabolites from Streptomyces Species.

Abstract

The focus of this study was the isolation of Streptomyces species which is antibiotic-producer from soil using a procedure for the selective growth of Streptomyces species. Actinomycetes are the most economically as well as biotechnologically valuable prokaryotes. An antagonistic microorganism (NN) was collected from soil from different fields in Dhaka and Munsigonj of Bangladesh. The microorganism was identified on the basis of its morphological characteristics as Streptomyces species. Bioactive metabolites were produced in the yeast-extract glucose broth media at 37.5°C temperature for 7 days. Considerable antibacterial activity of ethyl acetate and chloroform extract of NN was against Bacillus subtilis and Escherichia coli. This organism (NN) showed positive antibacterial activity against both pathogenic test organisms.