Evaluation of Hypoglycemic Activities of Herbal Drug Methi in Steptozotocin Induced Diabetic Rats

Abstract

Trigonella foenum-graecum, is commonly known as Fenugreek or Methi, is available in Bangladesh. Though there are various therapeutic approaches to reduce the metabolic disturbance of diabetes and its secondary complications, herbal formulation are now getting preference due to fewer side effects. The present study was carried out to evaluate the anti-diabetic properties of Trigonella foenum-graecum on type 2 diabetic model rats, effects of water suspension of Fenugreek (F), who were studied in Streptozotocin (STZ)-induced diabetic rats. Experimental diabetes was induced by injection a single dose of STZ (90mg/kg, i.p.). Adult male “Long Evans” rats were divided into three groups, for 28 days. Body weight, blood glucose level, were measured. The blood glucose level and body weight were the salient features recorded in diabetic control rats. The Fenugreek supplements significantly decreased the levels of blood glucose, near to the normal control value. Our data suggest that Fenugreek (methi) seeds powder supplementation may be beneficial for preventing diabetic complications.