Abstract:
Free radicals are associated with Diabetes and its complications. The present study was designed to investigate DPPH scavenging in-vitro antioxidant activity and antidiabetic activity on alloxan induced diabetic mice. Mice treated with extract dose at 300mg/kg p.o, showed a remarkable decrease ( ***p<0.001) of blood glucose concentration at 90min and 120min compared to diabetic control group and metformin was taken as a reference standard. In this study antioxidant activity of Citrullus lanatus was g/mlg/ml in contrast with ascorbic acid IC50 was 36.34 IC50 was 102.51 g/ml.g/ml in contrast with ascorbic acid IC50 was 36.34 g/ml.
